Atmospheric reactions of polycyclic aromatic hydrocarbons: facile formation of mutagenic nitro derivatives.
نویسندگان
چکیده
Directly active mutagens are formed on exposure of the promutagen benzo[a]pyrene to gaseous pollutants in smog. In simulated atmospheres containing 1 part per million nitrogen dioxide and traces of nitric acid, directly mutagenic nitro derivatives are readily formed from both benzo[a]pyrene and perylene, a non-mutagen in the Ames reversion assay. Possible formation of direct mutagens by such reactions on sample collection filters, in exhaust effluents, and in the atmosphere should be recognized.
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ورودعنوان ژورنال:
- Science
دوره 202 4367 شماره
صفحات -
تاریخ انتشار 1978